Our Facility
The Spring Point Project Source Animal Facility was opened in February 2007. In full operation, the facility is capable of housing approximately 100 to 150 young through adult pigs for use in for use in xenotransplantation research and future clinical applications. The state-of-the-art, biosecure research and development facility was designed to be flexible, allowing the introduction of animals via caesarean section or embryo transfer as well as internal natural reproduction on an ongoing basis. Special considerations were taken for proximity to potential pathogen sources and site design – surface materials, fixtures, mechanical, HVAC, electrical, supply water, waste (manure and effluent) removal, process controls and security.The facility features flexible handling, husbandry and reproduction of pigs under different conditions. While maintaining social grouping and interaction, the animals can be held in distinct units that are separated from each other’s air circulation, water supply and more in order to avoid cross-contamination. Also, it’s possible to conduct advanced reproduction methods, such as the birth of newborn piglets by caesarean section, artificial insemination, and embryo harvest and transfer.
One week after the official opening, the first piglets were delivered inside the barrier of the building by caesarean section. These and subsequent deliveries went very well, and all animals delivered fulfilled the designated pathogen-free status. Subsequently, an internal breeding program was initiated at the end of 2007, and the first piglets in the second generation were born at the end of April 2008. This second generation was particularly important because that’s when the animals could first be used for transplantation. |
“The potential impact of – Bernhard Hering, MD, |
